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MacOSX already includes the Python interpreter. However, if you install Python modules using MacPorts, you won’t be able to import them in your Python programs (ImportError: No module named <module name>).

The reason is that Apple’s Python doesn’t “see” the modules installed through MacPorts; you need to use MacPorts’s Python.

To see a list of available Python interpreters, run port select python. Then to choose e.g. MacPorts’s Python 2.6, run sudo port select python python26